Menu
  • About Us
  • News
  • Publications
  • Events
  • Careers
  • Contact
ProMabLogoProMabLogoProMabLogoProMabLogo
  • Login
  • 0 Items ($0.00)
    My Cart 1
  • Login
  • 0 Items ($0.00)
    My Cart 1
  • Top Sellers
    • CD19scFv-BEAM-CD28-CD3ZCD19scFv-BEAM-CD28-CD3ζ
    • CAR-T_Cell_MediumCAR-T Cell Medium
    • CD28-CD3_PM-T-Cell_Activation__Expansion_Beads_editCD28-CD3 Activation Beads
    • Cancer._Stem_PremiumCancer Stem Premium
    • P16_Antibody-v2P16 Antibody
  • Products
    • COVID19_8-04-2020COVID-19
    • primary-antibodyPrimary Antibody
      • Polyclonal Antibodies
      • Monoclonal Antibodies
    • Protein_IconFull-Length Protein
      • Recombinant Proteins
      • Natural Proteins
      • COVID-19 Research Products
    • CAR-T_iconCAR-T/CAR- NK
      • CAR-T cells
      • CAR-NK cells
      • T cell Activation Beads
      • Peripheral Blood Monocytes
    • Hempotological_products_IconHematological Products
      • Primary Cells
      • Non-Transduced T cells
      • Cell Media
      • Freezing Media
    • Icon_Product_mRNP_Lipid Nanoparticle_5_02_2022_finalmRNA-Lipid Nanoparticles
      • mRNA Products
      • LNP Products
    • stem-cell-iconCancer Stem Cells
      • Cancer Stem Cell Media
      • Hepatocellular Carcinoma (HCC)
      • Kidney Cancer
      • Ovarian Adenocarcinoma
      • Pancreatic Cancer
      • Prostate Cancer
      • Renal Cell Carcinoma
      • Lung Cancer Non-Small Cell (NSCLC)
      • Bladder Cancer
      • Breast Carcinoma
      • Colorectal Cancer
      • Glioblastoma
      • Head and Neck (H&N) Carcinoma
  • Services
    • v1-_Licensing_and_Distributing_CAR_Technology_7_22_2019_edit-1Licensing and Distributing CAR Technology
    • No_circles_-v2_Engineered_Cell_Lines-7_22_2019_finalCAR-T/CAR-NK Development
      • Custom CAR-T Cell Development
      • Custom CAR-NK Cell Development
      • Custom CAR-Macrophage Cell Development
      • Custom Gamma Delta T Cell Development
      • mRNA-LNP Gene Delivery
      • Lentivirus Production
      • Animal Research
      • Cancer Stem Cell Services
    • Cell_Based_Assay1_lastCell Based Assays
      • Flow Cytometry Services –
      • T Cell Specificity Assay
      • T Cell Activation & Proliferation Assay
      • Responsive T Cell Trafficking Assay
      • Cytokine Response Assay
      • Macrophage Polarization Assay
      • DC Migration Assay
    • Icon_ Services_mRNP_Lipid Nanoparticle_5_02_2022_finalmRNA-Lipid Nanoparticles
      • mRNA-LNP Gene Delivery
    • No_circles_-v3-Custom_Antibody_Engineering_7_22_2019_finalAntibody Engineering Services
      • Mouse Monoclonal Antibodies
      • Rabbit Monoclonal Antibodies
      • Human Monoclonal Antibodies
      • Recombinant Antibodies
      • Bispecific Antibodies
      • Antibody Humanization
      • Rabbit Polyclonal Antibodies
      • Hybridoma Sequencing
      • Antibody Production
    • No_circles_-v4-Protein_Expression_Services_7_22_2019_finalProtein Expression Services
      • E.coli Expression
      • Baculovirus Expression
      • Mammalian Expression
      • Stable Cell Line Development
      • Peptide Synthesis
      • Gene Synthesis Services
  • Protocols & Troubleshooting
    • Protocols
    • Technology
    • Troubleshooting
    • FAQ

SARS-CoV-2 (COVID-19) Research Products

Account
  • Home
  • Coronavirus
    • Custom Antibody Engineering Services
    • Mouse Monoclonal Antibodies
    • Rabbit Monoclonal Antibodies
    • Human Monoclonal Antibodies
    • Recombinant Antibodies
    • Bispecific Antibody Production
    • Rabbit Polyclonal Antibody Production
    • Antibody Production
    • Hybridoma Sequencing
    • Affinity Tune-Up & Humanization

DISCLAIMER: ProMab does not perform any COVID-19 related treatment.

ProMab has been dedicated to developing SARS-CoV-2 / COVID-19 Research Products which includes proteins, antibodies, and diagnostic research reagents.

SARS-CoV-2 (also known as 2019-nCoV and causes the COVID-19 disease), is a worldwide pandemic that emerged in December 2019 and is now reaching over 400,000 confirmed cases all over the globe. Belonging to the Betacoronavirus Genus, SARS-CoV-2 encodes the spike protein, envelope protein, membrane protein, and nucleocapsid protein in its viral structure. ProMab has developed a line of SARS-CoV-2 Research Products and related reagents.

The spike protein (S protein) contains two subunits, S1 and S2. S1 subunit contains a receptor binding domain (RBD), and the S2 subunit mediates membrane fusion. The spike protein is commonly used in research for vaccine and antibody development. SARS-CoV-2 uses the SARS-CoV receptor ACE2 for host cell entry (referenced here) which is another point of interest for COVID-19 R&D.

The Nucleocapsid protein (N protein) is a highly immunogenic phosphoprotein, commonly used as a marker in diagnostic asasys. Being the most abundant protein in the coronavirus, the N protein is often used for further viral research.

To assist in SARS-CoV-2 and COVID-19 research and development, some of these research products are ready to order or can be custom made, including but not limited to:

  • Nucleocapsid protein (N protein)
  • Spike protein (S protein)
  • Spike protein subunits (S1 and S2)
  • RBD domain of the S protein
  • RBD domain antibodies
  • ACE2 receptor protein
  • Stable cell line development
  • Different affinity tags (biotinylation, GFP, Fc tags, fusion tags for solubility, etc)

In addition to these ready to use proteins, we offer custom development such as producing stable cell lines and lentivirus. Our line of SARS-CoV-2 Research Products include our quantitative detection kits, with ProMab currently offering a SARS-CoV-2 N protein IgG ELISA Kit for research use only.

ProMab's Advantage In SARS-CoV-2 Research

Our extensive antibody development platform gives us a huge advantage over our competitors. We can develop and produce many research reagents for SARS-CoV-2.

Current available products:

Catalog # Product Name Expression System Tag Data Sheet
Pr40000 RBD-hFc Mammalian hFc Pr40000
Pr40001 Nucleocapsid protein fragment (NP-1)-His Bacterial His Pr40001
Pr40002 Nucleocapsid protein fragment (NP-2)-His Bacterial  His Pr40002
Pr40003 Nucleocapsid protein fragment (NP-3)-His Bacterial His  Pr40003
Pr40004 Spike protein 1 (S1) RBD-His Bacterial His  Pr40004
Pr40005 Spike protein 1 (S1) RBD-His Mammalian  His Pr40005
Pr40006 Nucleocapsid protein (full length) Mammalian His Pr40006
Pr40007 ACE2-hFc (ECD without signal peptide) Mammalian  hFc Pr40007
Pr40008 ACE2-hFc (full ECD) Mammalian hFc  Pr40008
Pr40009 ACE2-His Mammalian His Pr40009

 

Detection Kits

Catalog # Product Name Kit Type Detection Data Sheet
PMK-90001 SARS-CoV-2 IgG Detection Kit Quantitative ELISA IgG PMK-90001

 

Target Cell Lines

Catalog # Product Name Marker Cell Number Data Sheet
PM-HEK293-ACE2 ACE2 stable expression ACE2+ 1 x 10^6 cells/vial PM-HEK293-ACE2
Request A Quote

References

  1. Kruse R. Therapeutic strategies in an outbreak scenario to treat the novel coronavirus originating in Wuhan, China. 2020. F1000Research, 9:72 Last updated: 31 JAN 2020
  2. Xintian Xu, Ping Chen, Jingfang Wang, Jiannan Feng, Hui Zhou, Xuan Li, Wu Zhong, & Pei Hao. Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. 2020. Sci China Life Sci 63, https://doi.org/10.1007/s11427-020-1637-5

Other Custom Services:

mouse
Mouse monoclonal antibodies
cancer_opener_0
CAR-T development
CAR platform - Affinity Tune-Up and Humanization-2
Antibody Humanization

Sign up for news & promotions:

Products

  • Antibodies
  • Proteins
  • CAR T/NK Cells
  • Cell Lines
  • Cell Culture

Services

  • CAR-T/CAR-NK Development
  • Custom Antibodies
  • Synthesis and Expression
  • Clinical Research

Resources

  • Protocols
  • Technology
  • Troubleshooting
  • FAQ

Promab Biotechnologies

  • Promotions
  • About
  • News
  • Publications
  • Careers
  • Contact Us

Follow Us

Copyright © ProMab 2022 All Rights Reserved ProMab Biotechnologies, Inc. | 2600 Hilltop Drive, Building B, Suite C320, Richmond, CA 94806 USA | Email: info@promab.com