mTOR (phospho Ser2448) (PT0498R) PT® Rabbit mAb
Item Information
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Description
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008],
Product Overview
Entrez GenelD
2475
Clone#
PT0498R
Host / Isotype
Rabbit / IgG, Kappa
Species Reactivity
Human, Mouse, Rat
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage
-15°C to -25°C / 1 year (Do not store below -25°C)
Product Applications
WB (Western Blot)
1/2000 - 1/10000
IHC_P(Immunohistochemistry)
1/500 - 1/2000
ELISA
1/5000 - 1/20000
Product Image

Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-mTOR (phospho Ser2448) (PT0498R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.
Lane 1: Hela
Lane 2: MCF7
Lane 3: NIH-3T3
Predicted band size: 289kDa
Observed band size: 250kDa

Human colon carcinoma was stained with anti-mTOR (phospho Ser2448) (PT0498R) rabbit antibody

Human endometrium carcinoma was stained with anti-mTOR (phospho Ser2448) (PT0498R) rabbit antibody

Mouse colon was stained with anti-mTOR (phospho Ser2448) (PT0498R) rabbit antibody

Rat colon was stained with anti-mTOR (phospho Ser2448) (PT0498R) rabbit antibody
For Research Use Only. Not for use in diagnostic procedures.