HDAC4 (PT0600R) PT® Rabbit mAb

Item Information

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Price

Description

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008],

Product Overview

Entrez GenelD

9759

Clone#

PT0600R

Host / Isotype

Rabbit / IgG, Kappa

Species Reactivity

Human, Mouse, Rat

Formulation

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage

-15°C to -25°C / 1 year (Do not store below -25°C)

Product Applications

WB (Western Blot)

1/2000 - 1/10000

IHC_P(Immunohistochemistry)

1/50 - 1/200

ELISA

1/5000 - 1/20000

Product Image

Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-HDAC4 (PT0600R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: HEK293 Lane 2: Hela Lane 3: NIH-3T3 Lane 4: Rat womb Predicted band size: 119kDa Observed band size: 140kDa