Granzyme B (PT0581R) PT® Rabbit mAb

Item Information

Catalog #

Size

Price

Description

This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016],

Product Overview

Entrez GenelD

3002

Clone#

PT0581R

Host / Isotype

Rabbit / IgG, Kappa

Species Reactivity

Human

Formulation

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage

-15°C to -25°C / 1 year (Do not store below -25°C)

Product Applications

WB (Western Blot)

1/2000 - 1/10000

IHC_P(Immunohistochemistry)

1/1000 - 1/4000

ELISA

1/5000 - 1/20000

Product Image

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Granzyme B (PT0581R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Karpas-299 Lane 2: NK92 Predicted band size: 28kDa Observed band size: 37kDa