Filamin A (PT0388R) PT® Rabbit mAb

Item Information

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Price

Description

filamin A(FLNA) Homo sapiens The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009],

Product Overview

Entrez GenelD

2316

Clone#

PT0388R

Host / Isotype

Rabbit / IgG, Kappa

Species Reactivity

Human, Mouse, Rat

Formulation

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage

-15°C to -25°C / 1 year (Do not store below -25°C)

Product Applications

WB (Western Blot)

1/1000 - 1/5000

IHC_P(Immunohistochemistry)

1/4000 - 1/10000

ELISA

1/5000 - 1/20000

Product Image

Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-Filamin A (PT0388R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: HepG2 Lane 2: Mouse liver Predicted band size: 281kDa Observed band size: 281kDa