CD86 (PT0048R) PT® Rabbit mAb
Item Information
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Description
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011],
Product Overview
Entrez GenelD
942
Clone#
PT0048R
Host / Isotype
Rabbit / IgG, Kappa
Species Reactivity
Mouse
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage
-15°C to -25°C / 1 year (Do not store below -25°C)
Product Applications
WB (Western Blot)
1/500 - 1/5000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/5000 - 1/20000
Product Image
Immunofluorescence analysis of paraffin-embedded Mouse spleen. Primary Antibody was diluted at 1:200(4° overnight). an Multi colour-Fluorescence kit (RS0035, Immunoway). EDTA based antigen retrieval was used before Green tyramide signal amplification. DAPI (dark blue) was used as a nuclear counter stain. Microscopy and pseudocoloring of individual dyes was performed using a Slideviewer Imaging System (3D histech).
Mouse spleen was stained with anti-CD86 (PT0048R) rabbit antibody
For Research Use Only. Not for use in diagnostic procedures.