Bak (PT0551R) PT® Rabbit mAb

Item Information

Catalog #

Size

Price

Description

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008],

Product Overview

Entrez GenelD

578

Clone#

PT0551R

Host / Isotype

Rabbit / IgG, Kappa

Species Reactivity

Human, Mouse, Rat

Formulation

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage

-15°C to -25°C / 1 year (Do not store below -25°C)

Product Applications

WB (Western Blot)

1/2000 - 1/10000

IHC_P(Immunohistochemistry)

1/200 - 1/1000

ELISA

1/5000 - 1/20000

Product Image

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Bak (PT0551R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: K562 Lane 2: Hela Lane 3: A20 Predicted band size: 23kDa Observed band size: 23kDa