Tyrosinase Primary Antibody
Item Information
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Size
Price
Description
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
Product Overview
Entrez GenelD
7299
Aliases
OCA1A; OCAIA; SHEP3; TYR
Host / Isotype
Rabbit / IgG
Species Reactivity
Human, Monkey
Immunogen
Synthesized peptide derived from internal of human TYR.
Formulation
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Liquid in PBS containing 50% glycerol and 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Am J Med Genet A. 2009 Mar;149A(3):466-9.
2. J Invest Dermatol. 2009 Sep;129(9):2250-7.
2. J Invest Dermatol. 2009 Sep;129(9):2250-7.
Product Image
Western Blot
Figure 1: Western blot analysis using TRY Rabbit pAb against COS7 (1) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.