RUNX1 Primary Antibody
Item Information
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Price
Description
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Product Overview
Entrez GenelD
861
Aliases
AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1; RUNX1
Host / Isotype
Rabbit / IgG
Species Reactivity
Human, Mouse, Rabbit
Immunogen
Synthesized non-phosphopeptide derived from human RUNX1 around the phosphorylation site of serine 435.
Formulation
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Liquid in PBS containing 50% glycerol and 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Mol Med. 2010 Jul-Aug;16(7-8):247-53.
2. Mol Cell Biol. 2010 Aug;30(16):3943-55.
2. Mol Cell Biol. 2010 Aug;30(16):3943-55.
Product Image
Western Blot
Figure 1: Western blot analysis using RUNX1 Rabbit pAb against MOT4 (1), Jurkat (2), HepG2 (3), SW620 (4), MCF-7 (5) and PC-2 (6) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.