RUNX1 Primary Antibody

Item Information
Catalog # Size/Concentration Price
10004 100μl $308.00
Specification
AliasesAML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1; RUNX1
Product OrderR
Entrez GeneID861
FormulationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Liquid in PBS containing 50% glycerol and 0.03% sodium azide.
HostRabbit
IsotypeIgG
ImmunogenSynthesized non-phosphopeptide derived from human RUNX1 around the phosphorylation site of serine 435.
MW48kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C.  Learn More
Species ReactivityHuman, Mouse, Rabbit
Application
ELISA1/10000
Sequence
N/A
Catalog
10004
$308.00
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Images

Western Blot

Cell Culture Products
Figure 1: Western blot analysis using RUNX1 Rabbit pAb against MOT4 (1), Jurkat (2), HepG2 (3), SW620 (4), MCF-7 (5) and PC-2 (6) cell lysate.
Product Overview
Description Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
References (references)
References (references) 1. Mol Med. 2010 Jul-Aug;16(7-8):247-53.
2. Mol Cell Biol. 2010 Aug;30(16):3943-55.

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