OCT3 Primary Antibody

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Description

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Product Overview
Entrez GenelD
5460
Aliases
OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; MGC22487; POU5F
Host / Isotype
Rabbit / IgG
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from internal of human OCT3.
Formulation
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Liquid in PBS containing 50% glycerol and 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Cell. 2009 May 15;137(4):647-58.
2. Stem Cells. 2009 Jun;27(6):1265-75.
Product Image
Western Blot
Figure 1: Western blot analysis using OCT3 Rabbit pAb against Hela (1), MCF-7 (2), A431 (3) and HepG2 (4) cell lysate.
Figure 1: Western blot analysis using OCT3 Rabbit pAb against Hela (1), MCF-7 (2), A431 (3) and HepG2 (4) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.