MYC Primary Antibody

Item Information
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Description

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Product Overview
Entrez GenelD
9531
Aliases
BIS; BAG-3; CAIR-1; MGC104307; BAG3
Host / Isotype
Rabbit / IgG
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from internal of human MYC.
Formulation
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Liquid in PBS containing 50% glycerol and 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. J Cell Physiol. 2009 Feb;218(2):264-7.
2. FEBS Lett. 2009 Jan 22;583(2):401-6.
Product Image
Western Blot
Figure 1: Western blot analysis using MYC Rabbit pAb against HUVEC12 (1) cell lysate.
Figure 1: Western blot analysis using MYC Rabbit pAb against HUVEC12 (1) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.