BCL-2 Primary Antibody

Item Information
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Description

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.Tissue specificity: Expressed in a variety of tissues.

Product Overview
Entrez GenelD
596
Aliases
Bcl-2; BCL2
Host / Isotype
Rabbit / IgG
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from internal of human BCL-2.
Formulation
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Liquid in PBS containing 50% glycerol and 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. J Biol Chem. 2010 Mar 26;285(13):9770-9.
2. Pharmacogenomics J. 2010 Feb 16.
3. J Int Med Res. 2009 Nov-Dec;37(6):1868-76.
Product Image
Western Blot
Figure 1: Western blot analysis using BCL-2 Rabbit pAb against K562 (1), Jurkat (2) and THP-1 (3) cell lysate.
Figure 1: Western blot analysis using BCL-2 Rabbit pAb against K562 (1), Jurkat (2) and THP-1 (3) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer (left), recta cancer tissues (right) using BCL-2 Rabbit pAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer (left), recta cancer tissues (right) using BCL-2 Rabbit pAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.