ZBTB16 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesPLZF; ZNF145; ZBTB16
ProductOrderZ
Clone#5B3
Entrez GenelD7704
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human ZBTB16 expressed in E. Coli.
MW74kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
1-254
Catalog#: 30076
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Images
Western Blot
Figure 1: Western blot analysis using ZBTB16 mouse mAb against Hela (1) cell lysate.
Figure 1: Western blot analysis using ZBTB16 mouse mAb against Hela (1) cell lysate.
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of Hela cells using ZBTB16 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Figure 2: Immunofluorescence analysis of Hela cells using ZBTB16 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Product Overview
Description

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. Tissue specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.

References (references)
References (references)1. Cancer Res. 2008 Apr 15;68(8):2745-54
2. Immunity. 2008 Sep 19;29(3):391-403.