XRN2 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Overview
Entrez GenelD
22803
Aliases
N
Clone#
7C5B10
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human XRN2 (AA: 398-547) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1.EMBO J. 2012 May 30;31(11):2566-78.
2.DNA Seq. 2005 Apr;16(2):143-6.
2.DNA Seq. 2005 Apr;16(2):143-6.
Product Image
Elisa
![Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31011ea.jpg?v=1666701567)
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
![Figure 2:Western blot analysis using XRN2 mAb against human XRN2 (AA: 398-547) recombinant protein. (Expected MW is 43.1 kDa)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31011rwb.jpg?v=1666701567)
Figure 2:Western blot analysis using XRN2 mAb against human XRN2 (AA: 398-547) recombinant protein. (Expected MW is 43.1 kDa)
Western Blot
![Figure 3:Western blot analysis using XRN2 mAb against HEK293 (1) and XRN2 (AA: 398-547)-hIgGFc transfected HEK293 (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31011twb.jpg?v=1666701567)
Figure 3:Western blot analysis using XRN2 mAb against HEK293 (1) and XRN2 (AA: 398-547)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
![Figure 4:Western blot analysis using XRN2 mouse mAb against Raw264.7 (1), HEK293 (2), NTERA-2 (3), LNcap (4), HepG2 (5), HEK293 (6), and Hela (7) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31011lwb.jpg?v=1666701567)
Figure 4:Western blot analysis using XRN2 mouse mAb against Raw264.7 (1), HEK293 (2), NTERA-2 (3), LNcap (4), HepG2 (5), HEK293 (6), and Hela (7) cell lysate.
Immunohistochemical analysis
![Figure 5:Immunohistochemical analysis of paraffin-embedded colon cancer tissues using XRN2 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31011ihc-1.jpg?v=1666701567)
Figure 5:Immunohistochemical analysis of paraffin-embedded colon cancer tissues using XRN2 mouse mAb with DAB staining.
Immunohistochemical analysis
![Figure 6:Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using XRN2 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31011ihc-2.jpg?v=1666701567)
Figure 6:Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using XRN2 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.