WDFY3 Primary Antibody

Item Information
Catalog # Size/Concentration Price
31720 100ug $341.00
Specification
AliasesALFY; BCHS; MCPH18; ZFYVE25
Clone#2F7C2
Entrez GeneID23001
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenMouse IgG1
MW36.5kDa
Application
ELISA1/10000
IHC_P (Immunohistochemistry) 1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
Sequence
(AA: 3277-3526) expressed in E. Coli.
Catalog
31720
$341.00
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Images

Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Cell Culture Products

Figure 2: Western blot analysis using WDFY3 mAb against human WDFY3 (AA: 3277-3526) recombinant protein. (Expected MW is 54.2 kDa)

Cell Culture Products

Figure 3: Western blot analysis using WDFY3 mAb against HEK293 (1) and WDFY3 (AA: 3277-3526)-hIgGFc transfected HEK293 (2) cell lysate.

Cell Culture Products

Figure 4: Flow cytometric analysis of Hela cells using WDFY3 mouse mAb (green) and negative control (red).

Cell Culture Products

Figure 5: Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using WDFY3 mouse mAb with DAB staining.

Cell Culture Products
Tissue Array Results
Position Tissues Name Result Localization
Nucleus Cytoplasm Membrane
E9/10 Endometrial Cancer
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Product Overview
Description

This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.

References (references)
References (references) 1.Gynecol Obstet Invest. 2012;73(3):177-82.
2.Mol Cancer. 2010 Aug 6;9:211.

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