VIMP Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene encodes a member of the selenoprotein family, characterized by a selenocysteine (Sec) residue at the active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Overview
Entrez GenelD
55829
Aliases
SELS; ADO15; SBBI8; SEPS1; AD-015
Clone#
7F8G1
Host / Isotype
Mouse / IgG2b
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human VIMP (AA: 1-187) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1.Osteoarthritis Cartilage. 2015 Feb;23(2):210-6.
2.Blood Coagul Fibrinolysis. 2015 Mar;26(2):131-5.
2.Blood Coagul Fibrinolysis. 2015 Mar;26(2):131-5.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using VIMP mAb against human VIMP (AA: 1-187) recombinant protein. (Expected MW is 46.9 kDa)
Western Blot
Figure 3:Western blot analysis using VIMP mAb against HEK293 (1) and VIMP (AA: 1-187)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using VIMP mouse mAb against MCF-7 (1), PANC-1 (2), Jurkat (3), HepG2 (4), MOLT4 (5), U251 (6), and A431 (7) cell lysate.
Immunohistochemical analysis
Figure 5:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using VIMP mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 6:Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using VIMP mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.