VCAM1 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells.
Product Overview
Entrez GenelD
7412
Aliases
CD106; MGC99561; INCAM-100; DKFZp779G2333; VCAM1
Clone#
6G9
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human VCAM1 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Cell Adh Migr. 2009 Oct;3(4):369-72.
2. Arthritis Rheum. 2010 Jan;62(1):105-16.
2. Arthritis Rheum. 2010 Jan;62(1):105-16.
Product Image
Western Blot
Figure 1: Western blot analysis using VCAM1 mouse mAb against HUVEC (1) and EC (2) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human lung cancer (A) and colon cancer (B) using VCAM1 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded human Placenta tissues using VCAM1 mouse mAb
For Research Use Only. Not for use in diagnostic procedures.