Tyro3 Primary Antibody
Item Information
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Price
Description
Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.
Product Overview
Entrez GenelD
7301
Aliases
BYK; Brt; Dtk; RSE; Sky; Tif; FLJ16467
Clone#
6D6F10
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of Tyro3 (aa138-321) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
ICC (Immunocytochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Christoph Heiring, Bjon Dahlbok, and Yves A. Muller. J. Biol. Chem Feb 2004; 279: 6952 - 6958.
2. Sassan Hafizi, Anna Gustafsson, Jonas Stenhoff. Int J Biochem Cell Biol. 2005 Nov;37(11):2344-56.
2. Sassan Hafizi, Anna Gustafsson, Jonas Stenhoff. Int J Biochem Cell Biol. 2005 Nov;37(11):2344-56.
Product Image
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of Hela (Left) and MCF-7 (Right) cells using Tyro3 mouse mAb (green).
For Research Use Only. Not for use in diagnostic procedures.