TSLPR Primary Antibody

Item Information
Catalog # Size/Concentration Price
32001 100ug $358.00
Specification
AliasesCRL2; TSLPR; CRLF2Y
Clone#1E10D3
Entrez GeneID64109
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG1
ImmunogenPurified recombinant fragment of human TSLPR (AA: extra(23-231)) expressed in E. Coli.
MW42kDa
Application
ELISA1/10000
IHC_P (Immunohistochemistry) 1/200-1/1000
FCM (Flow Cytometry)1/200-1/400
WB (Western Blot)1/500 - 1/2000
Sequence
AA: 23-231
Catalog
32001
$358.00
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Images

ELISA

Cell Culture Products
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)

WESTERN BLOT

Cell Culture Products
Figure 2: Western blot analysis using TSLPR mAb against human TSLPR (AA: extra(23-231)) recombinant protein. (Expected MW is 27 kDa)

WESTERN BLOT

Cell Culture Products
Figure 3: Western blot analysis using TSLPR mAb against HEK293-6e (1) and TSLPR (AA: extra(23-231))-hIgGFc transfected HEK293-6e (2) cell lysate.

FLOW CYTOMETRY

Cell Culture Products
Figure 4: Flow cytometric analysis of THP-1 cells using TSLPR mouse mAb (green) and negative control (red).

IMMUNOHISTOCHEMISTRY

Cell Culture Products
Figure 5: Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using TSLPR mouse mAb with DAB staining.

IMMUNOHISTOCHEMISTRY

Cell Culture Products
Figure 6: Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using TSLPR mouse mAb with DAB staining.
Product Overview
Description

This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.

References (references)
References (references) 1,PLoS One. 2019 Dec 12;14(12):e0224652.2,Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019 Aug;27(4):1058-1063.

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