TSHB Primary Antibody
Item Information
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Size
Price
Description
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.
Product Overview
Entrez GenelD
7252
Aliases
TSH-B; TSH-BETA
Clone#
1D12G1
Host / Isotype
Mouse / IgG2b
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human TSHB (AA: 20-139) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Mol Biol Rep. 2012 Dec;39(12):10019-30.
2.Thyroid. 2010 Jun;20(6):639-45.
2.Thyroid. 2010 Jun;20(6):639-45.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using TSHB mAb against human TSHB (AA: 20-139) recombinant protein. (Expected MW is 16 kDa)
Flow cytometric
Figure 3:Flow cytometric analysis of Hela cells using TSHB mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 4:Immunohistochemical analysis of paraffin-embedded liver cancer tissues using TSHB mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 5:Immunohistochemical analysis of paraffin-embedded pancreas tissues using TSHB mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.