troponin T2 Primary Antibody
Item Information
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Price
Description
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Product Overview
Entrez GenelD
7139
Aliases
CMH2; RCM3; TnTC; cTnT; CMPD2; LVNC6
Clone#
1G1
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human troponin T2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
Cardiovasc Res. 2010 Jun 1;86(3):452-60.
Circ Cardiovasc Genet. 2009 Aug;2(4):306-13.
Circ Cardiovasc Genet. 2009 Aug;2(4):306-13.
Product Image
Western Blot
Figure 1: Western blot analysis using troponin T2 mAb against human troponin T2 (AA: 88-249) recombinant protein. (Expected MW is 25.1 kDa)
Flow cytometric
Figure 2: Flow cytometric analysis of MCF-7 cells using troponin T2 mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.