troponin T2 Primary Antibody
|Aliases||CMH2; RCM3; TnTC; cTnT; CMPD2; LVNC6|
|Formulation||Ascitic fluid containing 0.03% sodium azide. |
|Immunogen||Purified recombinant fragment of human troponin T2 expressed in E. Coli. |
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using troponin T2 mAb against human troponin T2 (AA: 88-249) recombinant protein. (Expected MW is 25.1 kDa)
Figure 2: Flow cytometric analysis of MCF-7 cells using troponin T2 mouse mAb (green) and negative control (red).
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
|References (references)||Cardiovasc Res. 2010 Jun 1;86(3):452-60. |
Circ Cardiovasc Genet. 2009 Aug;2(4):306-13.