TNFRSF11A Primary Antibody
Item Information
Catalog #
Size
Price
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
Product Overview
Entrez GenelD
8792
Aliases
FEO; OFE; ODFR; OSTS; PDB2; RANK; CD265; OPTB7; TRANCER; LOH18CR1
Clone#
8H8B2
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human TNFRSF11A (AA: extra 30-212) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Anticancer Res. 2016 Mar;36(3):1127-34.2.Int J Clin Exp Pathol. 2015 Feb 1;8(2):2249-58.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using TNFRSF11A mAb against human TNFRSF11A (AA: extra 30-212) recombinant protein. (Expected MW is 46 kDa)
Western Blot
Figure 3:Western blot analysis using TNFRSF11A mAb against HEK293 (1) and TNFRSF11A (AA: extra 30-212)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of Hela cells using TNFRSF11A mouse mAb (green) and negative control (red).
Flow cytometric
Figure 5:Flow cytometric analysis of HL-60 cells using TNFRSF11A mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.