Mouse Monoclonal Antibody to TNFRSF10A

Item Information

Catalog #

Size

Price

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

Product Overview

Entrez GenelD

8797

Aliases

DR4; APO2; CD261; TRAILR1; TRAILR-1

Clone#

4A4A9

Host / Isotype

Mouse / IgG1

Immunogen

Purified recombinant fragment of human TNFRSF10A (AA: extra 24-239) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

4℃; -20℃ for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

FCM (Flow Cytometry)

1/200 - 1/400

ELISA

1/10000

References

1.Int J Cancer. 2018 Jul 15;143(2):289-297. 2.BMC Cancer. 2018 Jul 31;18(1):777.

Product Image

Elisa

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Figure 2:Western blot analysis using TNFRSF10A mAb against human TNFRSF10A (AA: extra 24-239) recombinant protein. (Expected MW is 48.9 kDa)

Western Blot

Figure 3:Western blot analysis using TNFRSF10A mAb against HEK293-6e (1) and TNFRSF10A (AA: extra 24-239)-hIgGFc transfected HEK293-6e (2) cell lysate.

Flow cytometric analysis