TLT2

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesTLT2; TLT-2; C6orf76; dJ238O23.1
Clone#4F9D2
Entrez GenelD79865
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG2a
ImmunogenPurified recombinant fragment of human TLT2 (AA: extra 19-268) expressed in E. Coli.
MW35kDa
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
extra(19-268)
Catalog#: 32333
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Images
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using TLT2 mAb against human TLT2 (AA: 19-268) recombinant protein. (Expected MW is 30 kDa)
Figure 2:Western blot analysis using TLT2 mAb against human TLT2 (AA: 19-268) recombinant protein. (Expected MW is 30 kDa)
Western Blot
Figure 3:Western blot analysis using TLT2 mAb against HEK293-6e (1) and TLT2 (AA: 19-268)-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 3:Western blot analysis using TLT2 mAb against HEK293-6e (1) and TLT2 (AA: 19-268)-hIgGFc transfected HEK293-6e (2) cell lysate.
Immunohistochemical analysis
Figure 4:Immunofluorescence analysis of Hela cells using TLT2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Figure 4:Immunofluorescence analysis of Hela cells using TLT2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Immunofluorescence analysis
Figure 5:Flow cytometric analysis of HEK293 cells using TLT2 mouse mAb (green) and negative control (red).
Figure 5:Flow cytometric analysis of HEK293 cells using TLT2 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 6:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using TLT2 mouse mAb with DAB staining.
Figure 6:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using TLT2 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 7:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using TLT2 mouse mAb with DAB staining.
Figure 7:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using TLT2 mouse mAb with DAB staining.
Product Overview
Description

TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties.

References (references)
References (references)1,Brain Behav. 2020 Apr;10(4):e01573.
2,Front Immunol. 2020 Sep 11;11:2031.