TIP60 Primary Antibody
|Aliases||TIP; ESA1; PLIP; KAT5; cPLA2; HTATIP; ZC2HC5; HTATIP1|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human TIP60 (AA: 18-208) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 2:Western blot analysis using TIP60 mAb against human TIP60 (AA: 18-208) recombinant protein. (Expected MW is 47.9 kDa)
Figure 3:Western blot analysis using TIP60 mAb against HEK293 (1) and TIP60 (AA: 18-208)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Western blot analysis using TIP60 mouse mAb against Hela (1) cell lysate.
Figure 5:Flow cytometric analysis of Hela cells using TIP60 mouse mAb (green) and negative control (red).
|Description||The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.|
|References (references)||Anticancer Res. 2011 Jan;31(1):77-9.|
J Invest Dermatol. 2012 Nov;132(11):2632-41.