TIMP-3 Primary Antibody
Item Information
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Price
Description
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
Product Overview
Entrez GenelD
7078
Aliases
SFD; K222; K222TA2; HSMRK222
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human TIMP-3 expressed in E. Coli.
Formulation
Purified antibody in PBS containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Wei S et.al J Biol Chem.2005 Sep 23;280(38):32877-82.
2. Ogata T et.al J Vasc Surg. 2005 Jun;41(6):1036-42.
2. Ogata T et.al J Vasc Surg. 2005 Jun;41(6):1036-42.
Product Image
Western Blot
Figure 1: Western blot analysis using anti-TIMP3 polyclonal antiobdy against truncated TIMP3 recombinant protein.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (left) and breast carcinoma (right), showing cytoplasmic localization using anti-TIMP3 polyclonal antibody with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.