TIMP-3 Primary Antibody

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Description

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.

Product Overview
Formulation
Purified antibody in PBS containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
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Western Blot
Figure 1: Western blot analysis using anti-TIMP3 polyclonal antiobdy against truncated TIMP3 recombinant protein.
Figure 1: Western blot analysis using anti-TIMP3 polyclonal antiobdy against truncated TIMP3 recombinant protein.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (left) and breast carcinoma (right), showing cytoplasmic localization using anti-TIMP3 polyclonal antibody with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (left) and breast carcinoma (right), showing cytoplasmic localization using anti-TIMP3 polyclonal antibody with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.