TIMP-3 Primary Antibody
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
Purified antibody in PBS containing 0.03% sodium azide.
4°C; -20°C for long term storage
Figure 1: Western blot analysis using anti-TIMP3 polyclonal antiobdy against truncated TIMP3 recombinant protein.
Figure 2: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (left) and breast carcinoma (right), showing cytoplasmic localization using anti-TIMP3 polyclonal antibody with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.