TGFBR3 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Product Overview
Entrez GenelD
7049
Aliases
BGCAN; betaglycan
Clone#
1C5H11
Host / Isotype
Mouse / IgG2b
Species Reactivity
Human, Mouse
Immunogen
Purified recombinant fragment of human TGFBR3 (AA: 147-328 ) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Mol Biol Cell. 2011 May;22(9):1463-72.
2.Zhongguo Fei Ai Za Zhi. 2010 May;13(5):451-7.
2.Zhongguo Fei Ai Za Zhi. 2010 May;13(5):451-7.
Product Image
Western Blot
Figure 1: Western blot analysis using TGFBR3 mAb against human TGFBR3 recombinant protein. (Expected MW is 44.1 kDa)
Western Blot
Figure 2: Western blot analysis using TGFBR3 mouse mAb against Jurkat (1), HeLa (2), MCF-7 (3), F9 (4), SK-N-SH (5), and NIH3T3 (6) cell lysate.
Flow cytometric
Figure 3: Flow cytometric analysis of MOLT4 cells using TGFBR3 mouse mAb (green) and negative control (purple).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.