TGF beta1 Primary Antibody
Item Information
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Price
Description
TGF beta(transforming growth factor beta), with 390-amino acid protein (about 43 kDa), is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2,and beta3,are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.
Product Overview
Entrez GenelD
7040
Aliases
CED; DPD1; TGFB; TGFbeta; TGFB1
Clone#
4F9C10
Host / Isotype
Mouse / IgG2a
Species Reactivity
Human
Immunogen
Purified recombinant fragment of TGF beta1 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Delphine Boche, Colm Cunningham, Fabian Docagne. Neurobiol Dis. 2006 Feb 27
2. Shizuya Saika. Lab Invest. 2006 Feb;86(2):106-15
2. Shizuya Saika. Lab Invest. 2006 Feb;86(2):106-15
Product Image
Western Blot
Figure 1: Western blot analysis using TGF beta1 mouse mAb against truncated TGF beta1 recombinant protein.
For Research Use Only. Not for use in diagnostic procedures.