TFAP2B Primary Antibody
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using TFAP2B mAb against human TFAP2B (AA: 84-193) recombinant protein. (Expected MW is 38 kDa)
Figure 3:Western blot analysis using TFAP2B mAb against HEK293 (1) and TFAP2B (AA: 84-193)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Western blot analysis using TFAP2B mouse mAb against SK-N-SH (1) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.