TEC Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesPSCTK4
ProductOrderT
Clone#3A5
Entrez GenelD7006
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of TEC expressed in E. Coli.
MW74kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
90-240
Catalog#: 20380
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Images
Western Blot
Figure 1: Western blot analysis using TEC mouse mAb against TEC (aa90-240)-hIgGFc transfected HEK293 cell lysate (1).
Figure 1: Western blot analysis using TEC mouse mAb against TEC (aa90-240)-hIgGFc transfected HEK293 cell lysate (1).
Product Overview
Description

TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

References (references)
References (references)1. Blood. 2000 Nov 15;96(10):3406-13.
2. J Biol Chem. 1999 Jan 8;274(2):607-17.
3. Blood. 1998 Feb 1;91(3):940-8.