TCF3 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesE2A; ITF1; VDIR; bHLHb21; MGC129647; MGC129648; TCF3
ProductOrderT
Clone#6B8
Entrez GenelD6929
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human TCF3 expressed in E. Coli.
MW67.6kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
1-200
Catalog#: 30012
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Images
Western Blot
Figure 1: Western blot analysis using TCF3 mouse mAb against A549 (1), A431 (2), Hela (3), PANC-1 (4) and PC-3 (5) cell lysate.
Figure 1: Western blot analysis using TCF3 mouse mAb against A549 (1), A431 (2), Hela (3), PANC-1 (4) and PC-3 (5) cell lysate.
Flow cytometric
Figure 2: Flow cytometric analysis of A549 cells using anti-TCF3 mAb (green) and negative control (purple).
Figure 2: Flow cytometric analysis of A549 cells using anti-TCF3 mAb (green) and negative control (purple).
Product Overview
Description

Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.

References (references)
References (references)1.J Biol Chem. 2000 Oct 27;275(43):33567-73.
2.Mol Cell Biol. 2001 Mar;21(5):1866-73.
3.J Biol Chem. 2003 Jan 24;278(4):2370-6. Epub 2002 Nov 14.