TBX5 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesHOS; TBX5
ProductOrderT
Clone#7B11
Entrez GenelD6910
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of TBX5 expressed in E. Coli.
MW53kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
aa170-370
Catalog#: 20355
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Images
Western Blot
Figure 1: Western blot analysis using TBX5 mouse mAb against HepG2 cell lysate (1).
Figure 1: Western blot analysis using TBX5 mouse mAb against HepG2 cell lysate (1).
Product Overview
Description

TBX5, also known as T-box 5. It is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The TBX5 protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

References (references)
References (references)1. Physiol Genomics. 2004 Jul 8;18(2):129-40.
2. J Mol Cell Cardiol. 2003 Oct;35(10):1191-5.