TBX5 Primary Antibody

Item Information
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Price
Description

TBX5, also known as T-box 5. It is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The TBX5 protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

Product Overview
Entrez GenelD
6910
Aliases
HOS; TBX5
Clone#
7B11
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of TBX5 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Physiol Genomics. 2004 Jul 8;18(2):129-40.
2. J Mol Cell Cardiol. 2003 Oct;35(10):1191-5.
Product Image
Western Blot
Figure 1: Western blot analysis using TBX5 mouse mAb against HepG2 cell lysate (1).
Figure 1: Western blot analysis using TBX5 mouse mAb against HepG2 cell lysate (1).
For Research Use Only. Not for use in diagnostic procedures.