TAB2 Primary Antibody
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Description
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
Product Overview
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Image
Western Blot
Figure 1: Western blot analysis using TAB2 mAb against HEK293 (1) and TAB2(AA: 1-300)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 2: Flow cytometric analysis of HL-60 cells using TAB2 mouse mAb (green) and negative control (purple).
For Research Use Only. Not for use in diagnostic procedures.