TAB2 Primary Antibody
Item Information
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Price
Description
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
Product Overview
Entrez GenelD
23118
Aliases
CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; TAB2
Clone#
3B5
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human TAB2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1. J Clin Endocrinol Metab. 2006 Mar;91(3):1056-61.
2. Sci STKE. 2006 Oct 17;2006(357):re13.
3. Am J Hum Genet. 2010 Jun 11;86(6):839-49.
2. Sci STKE. 2006 Oct 17;2006(357):re13.
3. Am J Hum Genet. 2010 Jun 11;86(6):839-49.
Product Image
Western Blot
Figure 1: Western blot analysis using TAB2 mAb against HEK293 (1) and TAB2(AA: 1-300)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 2: Flow cytometric analysis of HL-60 cells using TAB2 mouse mAb (green) and negative control (purple).
For Research Use Only. Not for use in diagnostic procedures.