SYP Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesMRXSYP; SYP
ProductOrderS
Clone#7H12
Entrez GenelD6855
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of SYP expressed in E. Coli.
MW33.8kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Rat
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
224-313
Catalog#: 30032
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Images
Western Blot
Figure 1: Western blot analysis using SYP mouse mAb against rat brain tissue lysate.
Figure 1: Western blot analysis using SYP mouse mAb against rat brain tissue lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human Small Intestine, myenteric plexus tissues using anti-SYP mouse mAb
Figure 2: Immunohistochemical analysis of paraffin-embedded human Small Intestine, myenteric plexus tissues using anti-SYP mouse mAb
Product Overview
Description

Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.

References (references)
References (references)1. Cancer. 2007 Oct 15;110(8):1776-81.
2. J Gastroenterol Hepatol. 2008 Oct;23(10):1574-85.
3. Virchows Arch. 2009 Aug;455(2):125-32.