SUZ12 Primary Antibody

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Description

This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. (Provided by RefSeq) SUZ12 is overexpressed in several human tumors, including tumors of the colon, breast and liver.Tissue specificity: Overexpressed in breast and colon cancer.

Product Overview
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
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Western Blot
Figure 1: Western blot analysis using SUZ12 mAb against HEK293 (1) and SUZ12(AA: 533-739)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 1: Western blot analysis using SUZ12 mAb against HEK293 (1) and SUZ12(AA: 533-739)-hIgGFc transfected HEK293 (2) cell lysate.
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of U251 cells using SUZ12 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Figure 2: Immunofluorescence analysis of U251 cells using SUZ12 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Immunofluorescence analysis
Figure 3: Immunofluorescence analysis of MCF-7 cells using SUZ12 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Figure 3: Immunofluorescence analysis of MCF-7 cells using SUZ12 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
For Research Use Only. Not for use in diagnostic procedures.