STYK1 Primary Antibody

Item Information

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Description

Protein kinases (PKs) represent a well studied but most diverse protein superfamily. The covalent, reversible linkage of phosphate to serine, threonine, and tyrosine residues of substrate proteins by protein kinases is probably ubiquitous cellular mechanism for regulation of physiological processes. It is known to us that most signaling pathways impinge at some point on protein kinases. Here we report a human putative receptor protein kinase cDNA STYK1. The STYK1 cDNA is 2749 base pairs in length and contains an open reading frame encoding 422 amino acids. The STYK1 gene is mapped to human chromosome 12p13 and 11 exons were found. RT-PCR showed that STYK1 is widely expressed in human tissues.

Product Overview

Entrez GenelD

55359

Aliases

NOK; SuRTK106; DKFZp761P1010

Clone#

2H2F10

Host / Isotype

Mouse / IgG1

Species Reactivity

Human

Immunogen

Purified recombinant fragment of STYK1 expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

4°C; -20°C for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

IHC_P(Immunohistochemistry)

1/200 - 1/1000

ELISA

1/10000

References

1. Liu L, Yu XZ and Li TS, et al. Mol Biol Rep. 2003, Jun, 30(2):91-6.
2. Moriai R. , Kobayashi D.and Amachika T. , et al. Mol Biol Rep. 2007, Apr, 6.

Product Image

Western Blot

Figure 1: Western blot analysis using STYK1 mouse mAb against truncated STYK1 recombinant protein(1) and STYK1 (aa47-422)-hIgGFc transfected CHO-K1 cell lysate (2).

Immunohistochemical analysis

Figure 2: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (A), normal cerebrum tissues (B), breast infiltrating carcinoma (C) and breast infiltrating carcinoma (D), showing cytoplasmic localization using STYK1/NOK mouse mAb with DAB staining.

Immunohistochemical analysis