STAT6 Primary Antibody

Item Information

Catalog #

Size

Price

Description

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.

Product Overview

Entrez GenelD

6778

Aliases

STAT6B; STAT6C; D12S1644; IL-4-STAT; STAT6

Clone#

7D3

Host / Isotype

Mouse / IgG1

Species Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Purified recombinant fragment of human STAT6 expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

4°C; -20°C for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

ICC (Immunocytochemistry)

1/200 - 1/1000

ELISA

1/10000

References

1. Pediatr Nephrol. 2009 Mar;24(3):489-95.
2. Mol Immunol. 2009 Jun;46(10):2080-9.
3. Am J Hum Genet. 2009 Nov;85(5):628-42.

Product Image

Western Blot

Figure 1: Western blot analysis using STAT6 mouse mAb against HEK293 (1), NIH/3T3 (2), MCF-7 (3), Raw246.7 (4) and PC-12 (5) cell lysate.

Immunofluorescence analysis

Figure 2: Immunofluorescence analysis of Hela cells using STAT6 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin

For Research Use Only. Not for use in diagnostic procedures.