SSTR3 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants.
Product Overview
Entrez GenelD
6753
Aliases
SS3R; SS3-R; SS-3-R; SSR-28
Clone#
7H8E5
Host / Isotype
Mouse / IgG1
Species Reactivity
Human, Rat
Immunogen
Purified recombinant fragment of human SSTR3 (AA: 1-43) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1. J Gastroenterol Hepatol. 2008 Mar;23(3):424-9.
2. Cancer Biol Ther. 2004 Aug;3(8):726-30.
2. Cancer Biol Ther. 2004 Aug;3(8):726-30.
Product Image
Western Blot
Figure 1: Western blot analysis using SSTR3 mAb against human SSTR3 (AA: 1-43) recombinant protein. (Expected MW is 30.2 kDa)
Western Blot
Figure 2: Western blot analysis using SSTR3 mAb against HEK293 (1) and SSTR3 (AA: 1-43)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 3: Western blot analysis using SSTR3 mouse mAb against Hela (1), PANC-1 (2), PC-12 (3),SK-N-SH (4), U937 (5) and HepG2 (6) cell lysate.
Flow cytometric
Figure 4: Flow cytometric analysis of Hela cells using SSTR3 mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.