SRY Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesTDF; TDY; SRXX1; SRXY1
ProductOrderS
Clone#1G4
Entrez GenelD6736
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human SRY (AA:1-204) expressed in E. Coli.
MW23.9kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
full(1-204)
Catalog#: 30397
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Images
Western Blot
Figure 1: Western blot analysis using SRY mAb against human SRY recombinant protein. (Expected MW is 49.4 kDa)
Figure 1: Western blot analysis using SRY mAb against human SRY recombinant protein. (Expected MW is 49.4 kDa)
Western Blot
Figure 2: Western blot analysis using SRY mouse mAb against NTERA-2 (1) cell lysate.
Figure 2: Western blot analysis using SRY mouse mAb against NTERA-2 (1) cell lysate.
Flow cytometric
Figure 3: Flow cytometric analysis of HepG2 cells using SRY mouse mAb (green) and negative control (red).
Figure 3: Flow cytometric analysis of HepG2 cells using SRY mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using SRY mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using SRY mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 5: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using SRY mouse mAb with DAB staining.
Figure 5: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using SRY mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.

References (references)
References (references)1.J Biol Chem. 2009 Dec 18;284(51):35670-80. 2.FASEB J. 2009 Nov;23(11):4029-38.