SRC Primary Antibody

Item Information
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Description

SRC: v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian). This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Product Overview
Entrez GenelD
6714
Aliases
ASV; SRC1; c-SRC; p60-Src
Clone#
4F1E8
Host / Isotype
Mouse / IgG2b
Species Reactivity
Human
Immunogen
Purified recombinant fragment of SRC (aa10-193) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Pancreas. 2005 Oct;31(3):263-74.
2. Clin Exp Metastasis. 2005;22(3):195-204.
3. J Mol Biol. 2005 Oct 21;353(2):222-31.
4. J Cell Sci. 2006 Jan 1;119(Pt 1):47-55.
Product Image
Western Blot
Figure 1: Western blot analysis using SRC mouse mAb against truncated SRC-His recombinant protein (1) and PMA treated THP-1 cell lysate (2).
Figure 1: Western blot analysis using SRC mouse mAb against truncated SRC-His recombinant protein (1) and PMA treated THP-1 cell lysate (2).
For Research Use Only. Not for use in diagnostic procedures.