SOX2 Primary Antibody

Item Information

Catalog #

Size

Price

Description

SOX2: SRY (sex determining region Y)-box 2. Entrez Protein NP_003097. It is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Product Overview

Entrez GenelD

6657

Aliases

ANOP3; MCOPS3; MGC2413

Clone#

10F10C9

Host / Isotype

Mouse / IgG1

Species Reactivity

Human

Immunogen

Purified recombinant fragment of SOX2 (aa1-170) expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

4°C; -20°C for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

ELISA

1/10000

References

1. Exp Neurol. 2007 Apr;204(2):828-31.
2. Nature. 2008 Jan 10;451(7175):141-6.

Product Image

Western Blot

Figure 1: Western blot analysis using SOX2 mouse mAb against truncated Trx-SOX2 recombinant protein (1) and truncated MBP-SOX2(aa1-170) recombinant protein (2).

For Research Use Only. Not for use in diagnostic procedures.