SOX10 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.
Product Overview
Entrez GenelD
6663
Aliases
DOM; WS4; PCWH; WS2E; WS4C
Clone#
2E7E8
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human SOX10 (AA: 147-252) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. J Am Acad Dermatol. 2012 Oct;67(4):717-26.
2. J Neurooncol. 2006 Jan;76(2):115-27.
2. J Neurooncol. 2006 Jan;76(2):115-27.
Product Image
Western Blot
Figure 1: Western blot analysis using SOX10 mAb against human SOX10 recombinant protein. (Expected MW is 31.7 kDa)
Western Blot
Figure 2: Western blot analysis using SOX10 mAb against HEK293 (1) and SOX10 (AA: 147-252)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded breast cancer tissues using SOX10 mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.