SOX10 Primary Antibody
|Aliases||DOM; WS4; PCWH; WS2E; WS4C|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human SOX10 (AA: 147-252) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|IHC_P(Immunohistochemistry)||1/200 - 1/1000|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using SOX10 mAb against human SOX10 recombinant protein. (Expected MW is 31.7 kDa)
Figure 2: Western blot analysis using SOX10 mAb against HEK293 (1) and SOX10 (AA: 147-252)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Immunohistochemical analysis of paraffin-embedded breast cancer tissues using SOX10 mouse mAb with DAB staining.
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
|Description||This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. |
|References (references)||1. J Am Acad Dermatol. 2012 Oct;67(4):717-26. |
2. J Neurooncol. 2006 Jan;76(2):115-27.