SIRT6 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesSIR2L6
ProductOrderS
Clone#2G1E8
Entrez GenelD51548
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human SIRT6 (AA: 141-250) expressed in E. Coli.
MW39.1kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
141-250
Catalog#: 30895
Inquire
Contact us to order
Images
Elisa
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western Blot
Figure 2:Western blot analysis using SIRT6 mAb against human SIRT6 (AA: 141-250) recombinant protein. (Expected MW is 38 kDa)
Figure 2:Western blot analysis using SIRT6 mAb against human SIRT6 (AA: 141-250) recombinant protein. (Expected MW is 38 kDa)
Western Blot
Figure 3:Western blot analysis using SIRT6 mAb against HEK293 (1) and SIRT6 (AA: 141-250)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using SIRT6 mAb against HEK293 (1) and SIRT6 (AA: 141-250)-hIgGFc transfected HEK293 (2) cell lysate.
Product Overview
DescriptionThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.
References (references)
References (references)1.Asian Pac J Cancer Prev. 2014;15(17):7297-301.
2.Curr Top Med Chem. 2013;13(23):2991-3000.