SIRT2 Primary Antibody

Item Information
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Price
Description

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]

Product Overview
Entrez GenelD
22933
Aliases
SIR2; SIR2L; SIR2L2
Clone#
5H11H9
Host / Isotype
Mouse / IgG1
Immunogen
Mouse IgG1
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1.Neoplasia. 2016 Jun;18(6):339-46.
2.Oncogene. 2015 Nov 12;34(46):5699-708.
For Research Use Only. Not for use in diagnostic procedures.