SETDB1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesESET; KG1T; KMT1E; KIAA0067; H3-K9-HMTase4; SETDB1
ProductOrderS
Clone#5H6A12
Entrez GenelD9869
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human SETDB1 expressed in E. Coli.
MW180kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Mouse, Monkey
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
868-1211
Catalog#: 30132
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Images
Western Blot
Figure 1: Western blot analysis using SETDB1 mouse mAb against MCF-7 (1),T47D (2), HEK293 (3), JURKAT (4), NIH/3T3 (5), F9 (6), RAW246.7 (7) and Cos7 (8) cell lysate.
Figure 1: Western blot analysis using SETDB1 mouse mAb against MCF-7 (1),T47D (2), HEK293 (3), JURKAT (4), NIH/3T3 (5), F9 (6), RAW246.7 (7) and Cos7 (8) cell lysate.
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of LOVO cells using SETDB1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Figure 2: Immunofluorescence analysis of LOVO cells using SETDB1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Product Overview
Description

This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.

References (references)
References (references)1. Proteomics. 2005 Sep;5(14):3589-99.
2. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5308-13.
3. Mol Cell Biochem. 2007 Nov;305(1-2):35-44.