SETD2 Primary Antibody
Item Information
Catalog #
Size
Price
Description
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
Product Overview
Entrez GenelD
29072
Aliases
LLS; HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP
Clone#
4G11E6
Host / Isotype
Mouse / IgG1
Immunogen
Mouse IgG1
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Mech Ageing Dev. 2018 Mar;170:106-113.
2.J Phys Chem B. 2017 Jan 26;121(3):550-564.
2.J Phys Chem B. 2017 Jan 26;121(3):550-564.
For Research Use Only. Not for use in diagnostic procedures.