SERPINA7 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesTBG
ProductOrderS
Clone#1C3H11
Entrez GenelD6906
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human SERPINA7 (AA: 168-302) expressed in E. Coli.
MW46.3kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
168-302
Catalog#: 30555
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Images
Western Blot
Figure 1: Western blot analysis using SERPINA7 mAb against human SERPINA7 recombinant protein. (Expected MW is 41.4 kDa)
Figure 1: Western blot analysis using SERPINA7 mAb against human SERPINA7 recombinant protein. (Expected MW is 41.4 kDa)
Western Blot
Figure 2: Western blot analysis using SERPINA7 mAb against HEK293 (1) and SERPINA7 (AA: 168-302)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using SERPINA7 mAb against HEK293 (1) and SERPINA7 (AA: 168-302)-hIgGFc transfected HEK293 (2) cell lysate.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
DescriptionThere are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
References (references)
References (references)1. Gene. 2012 Sep 15;506(2):289-94.
2. Endocr Regul. 2010 Apr;44(2):43-7.