SEMAPHORIN-3A Primary Antibody
Item Information
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Description
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
Product Overview
Entrez GenelD
10371
Aliases
SEMA3A;HH16; SemD; COLL1; SEMA1; SEMAD; SEMAL; coll-1; Hsema-I; SEMAIII; Hsema-III
Clone#
1G6F9
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Synthesized peptide of human SEMAPHORIN-3A (AA: 359-372).
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1. Arthritis Res Ther. 2012 Jun 14;14(3):R146.
2. Birth Defects Res A Clin Mol Teratol. 2011 Sep;91(9):842-7.
2. Birth Defects Res A Clin Mol Teratol. 2011 Sep;91(9):842-7.
Product Image
Flow cytometric
Figure 1: Flow cytometric analysis of Hela cells using SEMAPHORIN-3A mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.