SEMAPHORIN-3A Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesSEMA3A;HH16; SemD; COLL1; SEMA1; SEMAD; SEMAL; coll-1; Hsema-I; SEMAIII; Hsema-III
ProductOrderS
Clone#1G6F9
Entrez GenelD10371
FormulationPurified antibody in PBS with 0.05% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenSynthesized peptide of human SEMAPHORIN-3A (AA: 359-372).
MW89kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
Sequence
359-372
Catalog#: 30724
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Images
Flow cytometric
Figure 1: Flow cytometric analysis of Hela cells using SEMAPHORIN-3A mouse mAb (green) and negative control (red).
Figure 1: Flow cytometric analysis of Hela cells using SEMAPHORIN-3A mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.

References (references)
References (references)1. Arthritis Res Ther. 2012 Jun 14;14(3):R146.
2. Birth Defects Res A Clin Mol Teratol. 2011 Sep;91(9):842-7.