RUNX1 Primary Antibody
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using RUNX1 mAb against human RUNX1 (AA: 237-337) recombinant protein. (Expected MW is 36.9 kDa)
Figure 3:Western blot analysis using RUNX1 mAb against HEK293 (1) and RUNX1 (AA: 237-337)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Flow cytometric analysis of K562 cells using RUNX1 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.