RUBCN Primary Antibody

Item Information
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Price
Description

The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Product Overview
Entrez GenelD
9711
Aliases
SCAR15; RUBICON; KIAA0226
Clone#
4F5B5
Host / Isotype
Mouse / IgG1
Immunogen
Purified recombinant fragment of human NR2C2 (AA: 62-356) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1.FEBS J. 2018 Apr;285(8):1379-1388.
2.Cerebellum. 2013 Dec;12(6):835-40.
For Research Use Only. Not for use in diagnostic procedures.